Rabbit Anti-DCP

Catalog Number : HZ71823          Quantity size :   0.1ml  （dilute with pH 7.4    0.01 M PBS or antibody diluent ）

Background:   Dcp1a is necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1. Dcp1a binds DCP1B, DCP2, RENT1 and SMAD4 and forms part of a cytoplasmic complex containing proteins involved in mRNA decay, including XRN1 and LSM1

pecificity :   

–        Anti-DCP is a rabbit polyclonal antibody unconjugated                

–         specific for DCP of human, mouse, rat          

–         use for western blotting,elisa,immunoprecipitation and immunohistochemistry

–         Protein G affinity chromatography purification, purity :>95%

–         Isotype:  IgG

–         mol wt:  70 kDa

Application :  

–        Western blotting 1:100-500                

–         Immunohistochemistry 1:100-500                 

–         ELISA 1:500-1000                  

–         Optimal working dilutions must  be determined by the end user.

Storage:  Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The  lyophilized antibody is stable at room temperature for at least one month and for greater  than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent  of antibody, the antibody is stable for at least six weeks at 2-4 ℃

 Important Note: This product as supplied is intended for research use only, not for use in  human, therapeutic or diagnostic applications.

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